How to prepare
Fasting for 8–12 hours before your blood draw is recommended. Leptin levels are influenced by food intake, sleep, and recent energy balance. Testing in the morning after an overnight fast gives the most consistent baseline. Collect before strenuous exercise.
After the test
Share your results with your GP, endocrinologist, or practitioner specialising in metabolic health. Leptin is one piece of a broader metabolic picture and is most useful when interpreted alongside insulin, fasting glucose, lipids, and clinical assessment.
Your test results will be available in your private dashboard. If there are any urgent issues, we'll let you know so you can follow up with your health professional.
Understanding results
Leptin is measured in nanograms per millilitre (ng/mL). Reference ranges vary significantly by sex and body composition:
- Women generally have higher leptin levels than men due to greater fat mass distribution.
- Men: typical range 2–5 ng/mL in lean individuals, but highly variable.
- Women: typical range 7–25 ng/mL in adults, but highly variable.
High leptin: In the context of excess body fat, high leptin may indicate leptin resistance. In lean individuals, high leptin can indicate other hormonal or inflammatory states.
Low leptin: Associated with very low body fat, severe caloric restriction, anorexia nervosa, or rare genetic leptin deficiency (extremely rare).
Leptin results must be interpreted alongside BMI, body composition, and other metabolic markers. There is no single threshold for clinical action. Context is everything.