Experiencing brain fog, memory issues, or unexplained fatigue and wondering if you're getting the active form of vitamin B12 your nerves and brain need to function optimally?
The Active Vitamin B12 Blood Test, also called the HoloTC Test, measures the form of B12 that your body can actually use. This test may help detect early deficiency that total B12 tests can miss, supporting the prevention of anaemia, fatigue, and nerve-related problems.
You will be emailed a referral to take to your local collection centre. If you ever have any questions, we're here to help.
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How It Works
Getting your health measured shouldn't be hard! We're here to help you every step of the way.
1
Order a test
Order the private test that suits you and your goals. After ordering, you will receive your referral by email.
2
Collect the sample
Attend one of our 4000+ partner collection centres throughout Australia. Search locations.
3
Receive your results
View all your lab results in your secure health dashboard. Easy!
Testimonials
What Our Customers Say
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Olga B.
New South Wales
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Getting a referral was easy. Laverty pathology accepted it. Bloody Good offers an affordable and convenient way to check essential blood markers.
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Adam O.
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Simple health checks in my control
I didn't know that private blood tests were an option. Tried this platform as the packages suited what I wanted for a good price. Easy to follow instructions, and super quick results. Platform provides more information than my gp's ever have on the tests and what the results meant. Would like more clinics to be able to test at (specifically Capital Pathology) but there is a decent network. Will continue to use.
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Very easy to use. Love that it stores your blood tests.
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Overview
Think of vitamin B12 as your body's master electrician and repair crew all rolled into one. This essential vitamin keeps your nerves firing properly, helps build healthy red blood cells, and ensures your DNA can repair itself effectively. The Active Vitamin B12 test specifically measures the form of B12 that your cells can actually use—not just what's floating around in your bloodstream. It's like checking whether you have working batteries in your flashlight, not just batteries sitting in a drawer.
This test is particularly valuable because it can catch B12 deficiency early, before you develop serious symptoms like nerve damage, severe fatigue, or cognitive problems. If you're experiencing unexplained numbness, memory issues, or persistent tiredness—or if you follow a vegetarian diet, have digestive issues, or take certain medications—this test can reveal whether low B12 is the culprit. Since B12 deficiency can cause irreversible nerve damage if left untreated, getting an accurate picture of your active B12 levels helps ensure your body's electrical system stays running smoothly for years to come.
Symptoms
Essential for individuals with neurological symptoms, dietary restrictions, absorption problems, or anyone needing comprehensive active B12 and neurological assessment.
Questions
Active B12 (holotranscobalamin) is the biologically available form of vitamin B12 that cells can actually use for nerve function and DNA synthesis.
Active B12 measures only the usable form, while total B12 includes inactive forms, making active B12 a more accurate indicator of deficiency.
Symptoms may include numbness, tingling, memory problems, fatigue, depression, balance problems, and in severe cases, irreversible nerve damage.
Causes include inadequate dietary intake (especially in vegetarians), pernicious anemia, gastrointestinal disorders, and certain medications affecting absorption.
Treatment typically includes B12 supplements (oral or injection), dietary modifications, and addressing underlying absorption problems.
Yes, severe B12 deficiency can cause irreversible neurological damage, making early detection and treatment crucial.
Dr. Vu Tran Bloody Good’s Chief Medical Officer
Biomarkers
Active Vitamin B12 (Holotranscobalamin)
How to prepare
No special preparation required. Inform healthcare provider of B12 supplements, dietary habits, and any factors that might affect B12 levels or interpretation.
After the test
Address B12 deficiency through appropriate supplementation (oral or injection), dietary modifications, and treatment of underlying absorption problems. Work with neurologists for complex cases.
Your test results will be available in your private dashboard. If there are any urgent issues, we'll let you know so you can follow up with your health professional.
Understanding results
Results show active B12 levels compared to normal ranges. Low levels may indicate B12 deficiency requiring supplementation and investigation of underlying causes.
Frequently Asked Questions
Most collection centres accept walk-ins. Some may require a booking - check details when you click on your chosen location.
If your test needs fasting, we’ll include that in your instructions after you order. Fasting usually means no food for 8–12 hours, but water is fine.
Just your pathology referral form (we email it to you)
Of course. Just maybe don’t bring the friend who faints at the sight of blood.
They’re the highly trained professionals who take your blood sample - with a steady hand and a sharp needle. They love blood, but don’t worry… they’re not vampires. Just legends who make blood tests quick, clean, and (almost) painless.
Some of our tests include Urine, Stool, Saliva and more. Each test will have a clear description on what sample you will need to give and instructions on how.
