How to prepare
No fasting is required. Eat and drink normally beforehand.
Timing within your menstrual cycle matters for this test. If you are being investigated for ovarian reserve or fertility, collection is typically done on day 2 or 3 of your cycle (where day 1 is the first day of full flow). For menopause assessment or in men, timing is less critical. Your practitioner will advise when to have this test done.
If you are taking oestrogen-containing medications or hormone therapy, let your practitioner know — these will directly affect your result. A healthcare professional will take a blood sample from a vein in your arm.
After the test
Share your results with your GP, gynaecologist, endocrinologist, or fertility specialist. Oestradiol is rarely interpreted alone — your practitioner will typically look at it alongside FSH, LH, AMH, and progesterone to build a full hormonal picture.
If you are investigating menopause or fertility, your practitioner will guide next steps based on your complete hormone profile and symptoms.
Your test results will be available in your private dashboard. If there are any urgent issues, we'll let you know so you can follow up with your health professional.
Understanding results
Results are reported in picomoles per litre (pmol/L). Reference ranges vary significantly by sex, age, and phase of the menstrual cycle — your result report will include the applicable range.
In women of reproductive age, oestradiol fluctuates throughout the cycle, peaking just before ovulation. Low oestradiol on day 2 or 3 may indicate diminished ovarian reserve or premature ovarian insufficiency. Persistently high oestradiol can be associated with ovarian cysts, endometriosis, or certain ovarian conditions. After menopause, oestradiol is expected to be very low.
In men, mildly elevated oestradiol can be associated with obesity, liver disease, certain medications, or conditions affecting testosterone conversion.
Your practitioner will interpret this result in the context of your cycle day, symptoms, other hormone markers, and clinical picture.