How to prepare
No fasting is required. You can eat and drink normally before your blood draw.
Let your GP know you are having this test. Ideally, it should be ordered as part of a broader clinical assessment rather than in isolation.
CA-125 can be elevated during menstruation, pregnancy, and shortly after gynaecological procedures. Where possible, avoid testing during your period for the most accurate baseline reading. If you are pregnant or recently postpartum, CA-125 is typically elevated and may not be clinically useful at that time.
After the test
Do not interpret a CA-125 result without input from your GP or gynaecologist. If you have a raised result, your doctor will likely arrange further investigation, which may include pelvic ultrasound, additional blood tests, or specialist referral.
If your result is within the normal range but you have ongoing symptoms, continue to discuss those symptoms with your GP. A normal CA-125 does not rule out all gynaecological conditions.
Your test results will be available in your private dashboard. If there are any urgent issues, we'll let you know so you can follow up with your health professional.
Understanding results
The standard reference range is below 35 U/mL, though some laboratories use slightly different thresholds. An elevated result does not confirm ovarian cancer. There are many causes of raised CA-125, including endometriosis, fibroids, liver disease, and pelvic inflammatory disease. A normal result does not rule out ovarian cancer, particularly in early stages.
Results must be interpreted by a doctor alongside your symptoms, medical history, and any imaging or other investigations. Postmenopausal women with levels above 35 U/mL generally warrant further evaluation.
