Bilirubin - Indirect (Unconjugated) Test

Bilirubin - Indirect (Unconjugated) Test

Name: Bilirubin - Indirect (Unconjugated) Test
Brand: Bloody Good
Price: 33.0 AUD
Availability: InStock

$33.00 AUD

Had a raised bilirubin result and want to find out whether it's from increased red blood cell breakdown, Gilbert's syndrome, or something else worth looking into?

Measures unconjugated (indirect) bilirubin, produced when red blood cells are broken down before liver processing. Elevated levels suggest haemolysis or reduced liver processing capacity, as seen in haemolytic anaemia and Gilbert's syndrome.

You will be emailed a referral to take to your local collection centre. If you ever have any questions, we're here to help.

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How It Works

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Order a test

Order the private test that suits you and your goals. After ordering, you will receive your referral by email.

Collect the sample

Attend one of our 4000+ partner collection centres throughout Australia. Search locations.

Receive your results

View all your lab results in your secure health dashboard. Easy!

Overview

Think of the Bilirubin Indirect (Unconjugated) Test as your body's recycling monitor. When your red blood cells reach the end of their natural lifespan, they break down and create a yellow waste product called bilirubin - it's like the leftover material from your body's cellular cleanup crew. This test specifically measures the "raw" form of bilirubin before your liver has had a chance to process it, giving us insight into whether your red blood cells are breaking down at a normal pace or if something is causing them to break down too quickly.

This test is particularly helpful if you're experiencing unexplained yellowing of your skin or eyes (jaundice), unusual fatigue, or if you have a family history of blood disorders. Elevated levels often point to conditions where red blood cells are being destroyed faster than normal - like certain types of anemia or genetic conditions such as Gilbert's syndrome, which is generally harmless but can cause mild jaundice during times of stress or illness. What makes this test valuable is that it helps your healthcare provider determine whether jaundice or other symptoms are related to blood disorders rather than liver problems, since these two types of issues require very different approaches to treatment and management.

Symptoms

To help investigate the cause of jaundice or elevated total bilirubin, assess for haemolytic anaemia, and evaluate whether a benign genetic variation such as Gilbert's syndrome may be contributing to raised bilirubin levels.

Questions

Gilbert's syndrome is a common, inherited condition where the liver processes bilirubin at a slightly reduced rate. It causes mild, intermittent rises in unconjugated bilirubin, often triggered by fasting, stress, or illness. It is benign and does not require treatment.
Haemolysis is the accelerated breakdown of red blood cells. When red cells are destroyed faster than normal, more unconjugated bilirubin is produced than the liver can process, leading to elevated levels. Causes include autoimmune conditions, inherited red cell disorders, certain medications, and infections.
Indirect (unconjugated) bilirubin is the form produced from red blood cell breakdown before the liver processes it. Direct (conjugated) bilirubin is the water-soluble form created by the liver for excretion. Elevated indirect bilirubin suggests a pre-hepatic cause such as haemolysis, while elevated direct bilirubin points toward liver or bile duct problems.
Yes. Many people with Gilbert's syndrome have no noticeable symptoms or only mild intermittent yellowing of the eyes. Elevated unconjugated bilirubin is often found incidentally on routine blood tests.
Indirect bilirubin is calculated by subtracting direct (conjugated) bilirubin from total bilirubin. Laboratories may report it as a calculated value rather than measuring it directly.
Not necessarily. Gilbert's syndrome is the most common cause of mildly elevated unconjugated bilirubin and is entirely benign. However, significantly raised levels can indicate haemolytic anaemia or other conditions that warrant investigation by your doctor.

Dr. Vu Tran
Bloody Good’s Chief Medical Officer

How to prepare

Fasting for at least four hours is recommended for the most accurate result. In people with Gilbert's syndrome, fasting and illness can temporarily raise unconjugated bilirubin levels. Avoid strenuous exercise the day before testing. Let your doctor know about all current medications, as some can affect red blood cell turnover or bilirubin metabolism.

After the test

Your doctor will review your result alongside total bilirubin, direct bilirubin, liver function tests, and a full blood count. If haemolytic anaemia is suspected, further testing such as a blood film, reticulocyte count, and haemolytic screen may follow. Gilbert's syndrome is benign and typically requires no treatment. If a blood disorder is identified, referral to a haematologist may be recommended.

Your test results will be available in your private dashboard. If there are any urgent issues, we'll let you know so you can follow up with your health professional.

Understanding results

Elevated indirect bilirubin with normal direct bilirubin points away from liver or bile duct obstruction and toward increased red blood cell breakdown or impaired hepatic uptake. In Gilbert's syndrome, mild elevation is typically isolated and intermittent, often triggered by fasting or illness. More substantial elevation may suggest haemolytic anaemia or another haematological condition, and your doctor will interpret results alongside a full blood count and other markers.

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Frequently Asked Questions

Do I need to book ahead?

Most collection centres accept walk-ins. Some may require a booking - check details when you click on your chosen location.

How do I know if I need to fast?

If your test needs fasting, we’ll include that in your instructions after you order. Fasting usually means no food for 8–12 hours, but water is fine.

What do I need to bring?

Just your pathology referral form (we email it to you)

Can I bring someone with me?

Of course. Just maybe don’t bring the friend who faints at the sight of blood.

What’s a phlebotomist?

They’re the highly trained professionals who take your blood sample - with a steady hand and a sharp needle. They love blood, but don’t worry… they’re not vampires. Just legends who make blood tests quick, clean, and (almost) painless.

What other samples may I need to provide for my test?

Some of our tests include Urine, Stool, Saliva and more. Each test will have a clear description on what sample you will need to give and instructions on how.