Immune System Health

Measures IgG4, linked to IgG4-related disease (IgG4-RD), a fibroinflammatory condition affecting the pancreas, bile ducts, kidneys, and other organs. Used alongside imaging and biopsy in specialist workups for IgG4-RD and autoimmune pancreatitis.

Measures IgM, the immune system's first-response antibody. Used to assess acute immune function, investigate immunodeficiency, and screen for Waldenstrom's macroglobulinaemia. Typically ordered alongside IgG and IgA as a full immunoglobulin panel.

At-home lactulose-mannitol challenge test measuring gut barrier function through timed urine collection. High lactulose recovery indicates increased intestinal permeability. Provides an objective measure of gut barrier integrity for practitioner review.

The Nickel Blood Test measures systemic nickel exposure. Nickel is the most common cause of metal contact allergy in Australia, and blood nickel testing is used to investigate occupational exposure, monitor nickel-containing joint implants, and assess levels in people with suspected nickel sensitivity.

Measures CA-125, a protein elevated in some women with ovarian cancer. Used primarily to monitor treatment response and disease surveillance in women already diagnosed with ovarian cancer, not as a general population screening test.

Measures copper inside red blood cells, a more stable indicator of tissue stores than serum copper. Useful when serum results are confounded by inflammation, pregnancy, or oestrogen use.

Measures zinc inside red blood cells, giving a more accurate picture of tissue-level zinc status than a standard serum test. Useful when serum zinc appears normal but symptoms of deficiency persist, or for monitoring zinc status in people with absorption conditions.

The Rheumatoid Factor (RF) Blood Test measures an autoantibody associated with rheumatoid arthritis, Sjogren's syndrome, and other autoimmune conditions. A positive result supports further investigation but is not diagnostic on its own, as RF can be positive in other conditions and negative in up to 30% of people with RA.

The Ross River Virus Serology Blood Test checks for IgM and IgG antibodies against Ross River Virus, a mosquito-borne infection common across Australia. IgM antibodies suggest recent infection while IgG indicates past exposure, and results are used alongside symptoms and travel history to assess whether RRV may be the cause of joint pain, fatigue, or rash.

The Secretory IgA Stool Test measures sIgA in stool, an antibody that lines the gut wall and forms a frontline barrier against pathogens and food antigens.

The Selenium Blood Test measures serum selenium, a trace mineral involved in thyroid hormone conversion, antioxidant defence, and immune function. Selenium intake in Australia varies by region due to differences in soil selenium content, making deficiency more common than in countries with uniformly selenium-rich soils.

Measures thyroglobulin, a protein produced exclusively by thyroid tissue. Used primarily to monitor for residual or recurrent thyroid cancer after thyroidectomy or radioiodine treatment, where levels are expected to be very low or undetectable.

Measures TSH, Free T4 and Free T3, the three key hormones used to assess how well the thyroid gland is working. Results can help identify an underactive or overactive thyroid, or flag that hormonal compensation is occurring elsewhere in the system.

Measures thyroid receptor antibodies (TRAb), which can stimulate the thyroid to overproduce hormones. Used to investigate Graves' disease, monitor treatment response, and assess thyroid-related risks during pregnancy.

Measures the combined level of albumin and globulin in blood. Abnormal levels can reflect changes in liver function, kidney function, nutritional status, or immune system activity. Routinely included in liver function panels and general health screens.

Measures anti-tissue transglutaminase IgA antibodies in stool, a marker of gut-level immune response to gluten. Elevated levels may suggest coeliac disease or non-coeliac gluten sensitivity. At-home collection kit.

Measures retinol (active vitamin A) in blood. Relevant for vision, immune function and skin health. Both deficiency and excess can cause problems, making testing useful for people with fat malabsorption conditions or those taking high-dose vitamin A supplements.

Measures plasma vitamin C (ascorbic acid), needed for collagen synthesis, immune function, iron absorption and antioxidant protection. Suboptimal levels are more common than many people assume, particularly in smokers, people with restricted diets and those under high physical or psychological stress.

Measures total 25-hydroxyvitamin D (D2 and D3 combined) from a finger-prick blood spot sample collected at home. The standard marker for assessing vitamin D status. Deficiency is common in Australia, particularly in winter and for people who spend most of their time indoors.

Measures 25-hydroxyvitamin D, the standard marker for vitamin D status. Vitamin D supports calcium absorption, bone mineralisation, immune function and muscle function. Deficiency is one of the most common nutritional deficiencies in Australia despite abundant sunshine.

Measures alpha-tocopherol (vitamin E) in blood. Vitamin E is a fat-soluble antioxidant protecting cell membranes and supporting immune and neurological function. Deficiency is uncommon with a balanced diet but can occur with fat malabsorption conditions, where prolonged deficiency may lead to peripheral neuropathy.

Measures serum zinc, the standard first-line test for zinc status. Zinc supports immune defence, wound healing, skin repair and the senses of taste and smell. Deficiency is common in people with restrictive diets, gastrointestinal conditions or increased physiological demands.