Over 90k Biomarkers Tested

Thyroxine-Binding Globulin (TBG) Blood Test

$54.00 AUD

Confused by conflicting thyroid test results, or wondering if unusual hormone levels might be related to the proteins that transport hormones in your blood?

Understand your thyroid hormone transport with our Thyroxine-Binding Globulin Blood Test. This protein carries thyroid hormones through your bloodstream, and measuring its levels can help explain abnormal thyroid function test results and guide an accurate thyroid health assessment.

Collection Location
Specimen Type

You will be emailed a referral to take to your local collection centre. If you ever have any questions, we're here to help.

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How It Works

Getting your health measured shouldn't be hard! We're here to help you every step of the way.

1
Order a test

Order a test

Order the private test that suits you and your goals. After ordering, you will receive your referral by email.

2
Collect the sample

Collect the sample

Attend one of our 4000+ partner collection centres throughout Australia. Search locations.

3
Receive your results

Receive your results

View all your lab results in your secure health dashboard. Easy!

Testimonials

What Our Customers Say

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Adam O. ACT

Simple health checks in my control

I didn't know that private blood tests were an option. Tried this platform as the packages suited what I wanted for a good price. Easy to follow instructions, and super quick results. Platform provides more information than my gp's ever have on the tests and what the results meant. Would like more clinics to be able to test at (specifically Capital Pathology) but there is a decent network. Will continue to use.

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Quick access to blood tests

BLOODY GOOD is a very efficient route to access blood testing for a visitor outside the Australian health system. It is quick with the necessary referral and documentation, and quick with results. Thank you

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Olga B. New South Wales

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Wayne NSW

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Overview

Think of TBG (Thyroid Binding Globulin) as your thyroid hormones' personal chauffeur service, responsible for safely transporting T4 and T3 hormones throughout your bloodstream. This protective carrier binds to about 75% of your circulating thyroid hormones, preventing them from breaking down too quickly while ensuring they're delivered exactly where your body needs them. Just like having too many or too few drivers affects how efficiently people get around a city, abnormal TBG levels can significantly impact how thyroid hormones circulate in your body, even when your thyroid gland is working perfectly fine.

This test becomes particularly valuable when your standard thyroid function tests show confusing results that don't match how you're actually feeling. When TBG levels are high, more thyroid hormone gets "tied up" in transport, making your total hormone levels appear elevated even though the amount of active hormone remains normal—and vice versa when TBG is low. Various factors like liver problems, certain medications, pregnancy, or even genetic variations can affect your TBG levels, so understanding your TBG status helps your doctor accurately interpret your other thyroid tests and determine whether any apparent abnormalities reflect true thyroid issues or simply changes in your body's hormone transport system.

Symptoms

Important for investigating discrepancies between thyroid function tests and symptoms. Essential for people with liver disease, kidney problems, or taking medications that affect protein levels. Valuable for interpreting thyroid tests during pregnancy, illness, or when using hormone medications.

Questions

  • While TBG doesn't directly affect thyroid function, it significantly influences total thyroid hormone measurements. Understanding TBG levels prevents misinterpretation of thyroid tests and inappropriate treatment.
  • Common causes include pregnancy, estrogen therapy, oral contraceptives, liver disease, and genetic variations. These conditions increase TBG production, leading to higher total thyroid hormone levels.
  • TBG deficiency itself doesn't cause symptoms because free thyroid hormone levels remain normal. However, it can make total thyroid hormone levels appear falsely low, potentially leading to unnecessary treatment.
  • Pregnancy typically doubles TBG levels due to increased estrogen, causing total T4 levels to rise significantly while free T4 levels remain normal. This is why free hormone tests are preferred during pregnancy.
  • Medication dosing should be based on free hormone levels and symptoms rather than total hormone levels, especially when TBG is abnormal. TBG measurement helps explain why total levels might be misleading.
  • Yes, TBG deficiency can be inherited and is more common in males due to X-linked inheritance. Family members should be tested if genetic TBG abnormalities are suspected.

Dr. Vu Tran
Bloody Good’s Chief Medical Officer

Biomarker Tested

How to prepare

No fasting required. Morning collection recommended for consistency with other thyroid tests. Avoid biotin supplements for 3 days before testing. Inform your healthcare provider about pregnancy, liver/kidney conditions, medications, and nutritional status as these significantly affect TBG levels.

After the test

Discuss results with your healthcare provider to understand how TBG levels affect interpretation of other thyroid tests. Abnormal TBG may require adjustment of thyroid hormone replacement dosing or switching to monitoring free hormone levels instead of total levels. Address underlying conditions affecting TBG such as liver disease or malnutrition.

Your test results will be available in your private dashboard. If there are any urgent issues, we'll let you know so you can follow up with your health professional.

Understanding results

Normal range: 12-28 mg/L (varies by laboratory). High TBG: May be caused by pregnancy, estrogen therapy, liver disease, or genetic factors. Low TBG: Often due to liver disease, kidney disease, malnutrition, certain medications, or genetic deficiency. Results help interpret total T4 and T3 levels more accurately.

Frequently Asked Questions

Most collection centres accept walk-ins. Some may require a booking - check details when you click on your chosen location.

If your test needs fasting, we’ll include that in your instructions after you order. Fasting usually means no food for 8–12 hours, but water is fine.

Just your pathology referral form (we email it to you)

Of course. Just maybe don’t bring the friend who faints at the sight of blood.

They’re the highly trained professionals who take your blood sample - with a steady hand and a sharp needle. They love blood, but don’t worry… they’re not vampires. Just legends who make blood tests quick, clean, and (almost) painless.

Some of our tests include Urine, Stool, Saliva and more. Each test will have a clear description on what sample you will need to give and instructions on how.