Family history of breast or ovarian cancer
Overview
Family history of breast or ovarian cancer refers to having blood relatives who have been diagnosed with breast cancer, ovarian cancer, or both types of cancer. This genetic predisposition increases an individual's risk of developing these cancers due to inherited gene mutations such as BRCA1 and BRCA2.
Common Causes
Having close relatives with breast or ovarian cancer can increase your risk due to inherited genetic mutations, particularly in the BRCA1 and BRCA2 genes. These genetic changes can be passed down through families and significantly raise the likelihood of developing these cancers. Environmental factors shared within families, such as similar lifestyle habits or exposures, may also contribute to increased risk patterns across generations.
Severity Levels
Mild: One or two distant relatives (like great-aunts or second cousins) diagnosed with breast or ovarian cancer, typically at older ages.
Moderate: Multiple relatives on one side of the family affected, or one close relative (parent, sibling, child) diagnosed after age 50.
Severe: Multiple close relatives affected, diagnosis at young ages (under 50), male relatives with breast cancer, or known BRCA gene mutations in the family.
Medical Attention
You should consult with a healthcare provider or genetic counselor if you have multiple close relatives with breast or ovarian cancer, especially if they were diagnosed at a young age. Seek medical advice if you have relatives with both breast and ovarian cancers, or if there's a known genetic mutation in your family. Consider genetic counseling if you're planning a family or making decisions about preventive care, as early screening and risk-reduction strategies may be recommended based on your family history.
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