Testosterone measured by Liquid Chromatography-Mass Spectrometry (LCMS)
Testosterone is a key hormone affecting energy, mood, and physical development in both men and women. Testing it helps understand hormonal balance and overall health.

Hormone
Overview
Testosterone is a hormone that plays a crucial role in the body for both men and women. In men, it's primarily produced in the testes and is responsible for developing male characteristics like deeper voice, muscle mass, and body hair. In women, it's produced in smaller amounts by the ovaries and adrenal glands, contributing to bone strength, muscle mass, and overall well-being. Measuring testosterone levels provides insight into hormonal balance, affecting energy levels, mood, and various bodily functions. The most accurate way to measure testosterone is through Liquid Chromatography-Mass Spectrometry (LCMS), a precise lab technique that ensures reliable results. This test helps diagnose conditions like low testosterone levels in men, polycystic ovary syndrome (PCOS) in women, and other hormonal imbalances.
Testing Levels:
- High (35 nmol/L) - If testosterone levels are higher than normal, it could indicate certain health issues. In men, excessively high levels might be due to anabolic steroid use or rare conditions like tumours in the testes or adrenal glands. In women, high testosterone levels can be a sign of PCOS, adrenal disorders, or other hormonal imbalances. Symptoms may include acne, excessive hair growth, and irregular menstrual cycles in women. It's important to consult a healthcare provider to determine the underlying cause and appropriate treatment.
- Mid - Testosterone levels within the normal range indicate a balanced hormonal state. For men, this means healthy sexual development, energy levels, and muscle mass. For women, it contributes to bone strength, mood, and overall health. Maintaining this balance is essential for well-being and normal bodily functions.
When testosterone levels are near the upper limit, it may not immediately signal a problem, but it's worth monitoring. In men, it might reflect a peak in natural production or the influence of lifestyle factors like intense exercise. In women, levels close to the upper limit could suggest early signs of hormonal imbalance or PCOS. Keeping an eye on symptoms and possibly re-testing can help ensure that levels remain within a healthy range.
Levels near the lower limit may suggest the beginning of a decline in testosterone. In men, this could lead to symptoms like reduced energy, decreased muscle mass, or low libido. In women, it might affect mood or bone density. Lifestyle changes such as improved diet, regular exercise, and stress management can help maintain healthy levels. If symptoms are present, it's advisable to consult a healthcare provider for further evaluation. - Low (10 nmol/L) - Low testosterone levels can have various effects. In men, it might cause fatigue, depression, loss of muscle mass, or decreased sexual desire. In women, low levels could lead to decreased bone density, mood swings, or reduced libido. Causes might include hormonal disorders, chronic illnesses, or natural aging. Medical evaluation is important to identify the cause and discuss possible treatments, which may include hormone replacement therapy or lifestyle modifications.
Why We Test Testosterone measured by Liquid Chromatography-Mass Spectrometry (LCMS)
Testing testosterone levels can help diagnose hormonal imbalances that may affect your health and quality of life. If you're experiencing symptoms like fatigue, mood changes, decreased muscle mass, or changes in libido, this test can provide valuable insights. It's also useful for monitoring treatment effectiveness if you're receiving hormone therapy.
What Affects It
Several factors can influence testosterone levels. Age is a significant one; levels naturally decline as people get older. Lifestyle choices like diet, exercise, stress, and sleep patterns can also impact testosterone. Certain medical conditions such as obesity, liver or kidney disease, and hormonal disorders can alter levels. Medications like steroids or hormone therapies may affect the results too. For accurate measurement, it's important to consider these factors, as they can cause testosterone levels to fluctuate.
How to Improve
If testosterone levels are high, addressing the underlying cause is important. This might involve adjusting medications, treating hormonal disorders, or making lifestyle changes. For levels that are close to being high, monitoring and possibly reducing factors like stress or excessive exercise may help. If levels are low or nearing low, lifestyle changes like regular physical activity, a balanced diet, sufficient sleep, and stress reduction can boost testosterone. In some cases, medical treatments like hormone replacement therapy might be recommended by a healthcare provider. Regular monitoring and professional guidance are key to maintaining healthy testosterone levels.
Common Name: Testosterone (LCMS)

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