Parathyroid hormone

Parathyroid hormone regulates calcium and phosphorus levels, essential for healthy bones and proper muscle and nerve function.

📋 About This Biomarker

Parathyroid hormone (PTH) is like the body's calcium regulator, produced by the small parathyroid glands located in your neck. Think of it as a thermostat for calcium levels, ensuring they stay within a healthy range. Calcium isn't just important for strong bones and teeth; it's also crucial for muscle movement, nerve function, and blood clotting.PTH manages calcium levels by controlling how much calcium is absorbed from your food, how much is released from your bones, and how much is excreted by your kidneys. It also influences the activation of vitamin D, which helps your body absorb calcium. By monitoring PTH levels, we gain insight into how well your body is balancing calcium and phosphorus - minerals vital for many bodily functions. Whether everything is in harmony or starting to shift, keeping an eye on PTH helps us understand your bone health and overall mineral balance.

🎯 Why We Test This

Testing PTH levels helps assess how well your body is managing calcium and phosphorus balance. It's particularly important if you have symptoms of high or low calcium levels, such as fatigue, muscle weakness, cramps, or bone pain. It aids in diagnosing conditions like hyperparathyroidism or hypoparathyroidism and guides treatment decisions. For those with kidney disease or who've had thyroid or parathyroid surgery, monitoring PTH is crucial to manage their health effectively.

⚠️ What Affects It

Several factors can influence PTH levels. Low calcium intake or vitamin D deficiency can cause PTH levels to rise as the body tries to maintain normal calcium levels. Kidney function plays a significant role because kidneys help convert vitamin D into its active form and excrete excess phosphorus. Certain medications, like lithium or steroids, can impact PTH levels. Conditions such as hyperparathyroidism (overactive parathyroid glands) or hypoparathyroidism (underactive glands) directly affect PTH production. Even lifestyle factors like diet, sun exposure (which affects vitamin D levels), and age can influence PTH levels.

📈 How to Improve

If PTH levels are high or approaching high, increasing your intake of calcium and vitamin D through diet or supplements (as advised by a healthcare professional) can help. Addressing underlying issues like vitamin D deficiency or kidney problems is also important. In cases of overactive parathyroid glands, medication or surgery might be necessary.If PTH levels are low or near the lower limit, reducing excessive calcium or vitamin D intake may be recommended. Ensuring you're not over-supplementing and discussing your medications with a doctor can help bring PTH levels back to normal. Regular monitoring and working with a healthcare provider are key to maintaining healthy PTH levels and overall mineral balance.

📊 Understanding Your Results (pmol/L)

Low (< 1.6 pmol/L)
Low PTH levels suggest hypoparathyroidism, where the parathyroid glands are underactive. This leads to low calcium levels in your blood, which can cause symptoms like tingling in your fingers and toes, muscle cramps, or even more severe muscle spasms. It's as if the calcium 'thermostat' is set too low, and your body isn't maintaining the necessary calcium levels. Treatment usually involves calcium and vitamin D supplements to restore balance.
Optimal (1.6 - 6.9 pmol/L)
PTH levels within the normal range mean your parathyroid glands are functioning properly, and your body is maintaining a healthy balance of calcium and phosphorus. This balance supports strong bones, proper muscle function, and overall well-being. It's a good sign that your body's calcium 'thermostat' is set just right. If your PTH levels are nearing the upper limit, it could be an early indication that your parathyroid glands are starting to become overactive or that your body isn't absorbing enough calcium or vitamin D. It's like a gentle alert to check your diet, ensure you're getting enough calcium and vitamin D, and possibly evaluate kidney function. Early action can help prevent more serious issues related to bone density and mineral balance. When PTH levels are near the lower limit, it may indicate that your parathyroid glands are producing slightly less hormone than usual. This could happen if your calcium levels are higher than normal, perhaps due to excessive calcium or vitamin D intake. While it might not cause immediate problems, it's a signal to monitor your calcium intake and possibly adjust any supplements you're taking to prevent potential issues.
High (> 6.9 pmol/L)
Elevated PTH levels suggest that your parathyroid glands are overactive, a condition known as hyperparathyroidism. This can lead to high calcium levels in your blood, potentially causing symptoms like tiredness, muscle weakness, bone or joint pain, kidney stones, or mood changes. High PTH can also be a response to low calcium or vitamin D levels - your body produces more PTH to try to increase calcium levels. Chronic kidney disease can also cause elevated PTH. Identifying high PTH levels is important to address underlying issues and prevent complications related to calcium imbalance.
Also known as: PTH