Nickel

Overview

Nickel is a naturally occurring metal that can be measured in the body as a biomarker to assess exposure to this element from various sources. The human body normally contains trace amounts of nickel, but elevated levels may indicate excessive exposure from occupational settings, contaminated water, certain foods, or contact with nickel-containing materials like jewelry, coins, or industrial equipment. Nickel can be detected through blood, urine, or hair samples, with urine testing being the most common method for assessing recent exposure. While nickel plays a minor role in some biological processes, it is primarily considered a potential toxin and allergen. Elevated nickel levels may be associated with allergic contact dermatitis, respiratory issues in occupational settings, or other health concerns related to metal toxicity. Monitoring nickel levels can be particularly important for individuals working in industries such as electroplating, welding, or battery manufacturing, as well as those experiencing unexplained allergic reactions or symptoms that might be related to metal exposure.

Testing Levels:

• High ( ) -
  
  
• Mid -
  
  
• Low ( ) -

Why We Test Nickel

Testing for nickel levels may be important if you have suspected occupational exposure from metalworking, welding, or battery manufacturing industries. Elevated nickel can indicate potential toxicity risks including respiratory problems, skin sensitization, and possible carcinogenic effects from chronic exposure. This biomarker is particularly valuable for workers in stainless steel production, electroplating, or nickel refining facilities where airborne nickel particles pose health hazards. Additionally, testing may be warranted if you have unexplained allergic contact dermatitis, as nickel is one of the most common causes of metal allergies.

What Affects It

Factors influencing nickel levels include occupational exposure (welding, electroplating, stainless steel production), dietary intake (nuts, chocolate, legumes, whole grains), use of nickel-containing jewelry or dental materials, and smoking. Medical conditions such as kidney disease can affect nickel excretion, while certain medications and supplements may contain trace amounts of nickel. Environmental exposure through contaminated water or air pollution can also impact nickel biomarker levels.

How to Improve

For elevated nickel levels, reducing exposure to nickel-containing items like jewelry, cookware, and occupational sources is essential. Following a low-nickel diet by avoiding foods like chocolate, nuts, legumes, and canned foods can help. Ensuring adequate zinc and iron intake may compete with nickel absorption. For low nickel levels, which are rare and typically not concerning, maintaining a balanced diet with varied food sources is usually sufficient. Regular monitoring of occupational exposure and consultation with a healthcare provider help ensure nickel levels remain within safe ranges and identify any underlying exposure sources.

Common Name: Nickel