Dehydroepiandrosterone Sulfate (DHEA-S)

DHEAS is like your body’s internal youth serum, enhancing vitality and playing a role in building muscle.

📋 About This Biomarker

Think of DHEAS as your body’s own natural energizer. Produced by your adrenal glands, it’s one of the most abundant circulating steroids in humans and serves as a precursor to both male and female sex hormones (androgens and estrogens). Its levels peak in your mid-20s and gradually decline with age, which is why it’s often linked to aging. DHEAS boosts energy, supports muscle growth, enhances immune function, and improves mood and libido. It’s like the Swiss Army knife of hormones - versatile and fundamental for maintaining youthful vigor and health.

🎯 Why We Test This

Monitoring DHEAS levels can provide insights into your adrenal function and general health status. It’s particularly relevant if you’re experiencing symptoms such as fatigue, a decrease in muscle mass, low libido, or issues related to hormonal imbalances. Testing DHEAS can also be important for assessing how well your body is aging and can guide interventions to help maintain your quality of life as you grow older.

⚠️ What Affects It

Several factors can influence DHEAS levels, including age, stress, nutrition, exercise habits, and overall health status. Certain medications and chronic conditions such as depression or anorexia can also affect the production of DHEAS.

📈 How to Improve

Managing DHEAS levels generally involves addressing adrenal health through lifestyle changes. Regular exercise, a nutritious diet, and managing stress are crucial. For low levels, DHEAS supplements might be considered under medical supervision to help improve levels and counteract deficiency symptoms. If levels are unusually high, it’s important to investigate further with your healthcare provider to rule out adrenal gland disorders.

📊 Understanding Your Results (umol/L)

Low (< 0.7 umol/L)
Low levels of DHEAS can make you feel like you’re running low on fuel. This can manifest as increased fatigue, a decrease in muscle mass and strength, lessened immune function, and reduced libido. Low DHEA is common in older adults but can also indicate adrenal insufficiency or pituitary problems in younger people. Certain medicines and natural preparations, such as insulin, cortisone, fish oil and vitamin E, also contribute to a lowering of DHEAS.
Optimal (0.7 - 12 umol/L)
Normal DHEAS levels suggest that your adrenal glands are functioning properly, providing a good balance of hormones that support overall health, energy levels, and well-being. It’s a sign that your body’s natural aging process is on track, and your hormonal environment is stable. DHEAS levels that are creeping up toward the high end can indicate your adrenal glands are a bit overactive. It’s often not a cause for alarm, but it might be a cue to check on other hormone levels and ensure everything is balanced. When DHEA levels are hovering near the lower threshold, it might indicate a dip in adrenal efficiency, which can reduce your overall energy and vitality. It’s beneficial to look at lifestyle factors such as stress, diet, and sleep quality, as improvements in these areas can help boost your DHEAS levels.
High (> 12 umol/L)
Elevated DHEAS levels might give you a temporary boost but can also signal underlying issues like adrenal hyperplasia or rarely, adrenal tumors. High DHEAS can lead to symptoms of excessive androgen production, such as acne, increased body hair, and in women, irregular menstrual cycles.
Also known as: DHEAS, DHEA Sulphate, DHEA-Sulphate