Have thyroid cancer history, previous thyroid surgery, or abnormal thyroid function and need assessment of thyroid tissue activity for ongoing monitoring?
The Thyroglobulin Blood Test measures a protein made by the thyroid gland. After thyroid surgery or treatment for thyroid cancer, this test may help check for recurrence. It can also be used alongside antibody tests to assess thyroid function and possible autoimmune activity.
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The Thyroglobulin Blood Test measures a protein made by the thyroid gland. After thyroid surgery or treatment for thyroid cancer, this test may help check for recurrence. It can also be used alongside antibody tests to assess thyroid function and possible autoimmune activity.
The Thyroglobulin test measures a special protein that acts like your thyroid's unique fingerprint—it's only made by thyroid tissue, nowhere else in your body. Think of thyroglobulin as your thyroid's storage container for thyroid hormones, quietly doing its job in the background and releasing tiny amounts into your bloodstream during normal function. This test works by checking how much of this protein is circulating in your blood, giving doctors valuable insight into what your thyroid tissue is up to.
This test is especially important for people who've had thyroid cancer, as it serves as an early warning system to detect if cancer cells are trying to make a comeback. When thyroglobulin levels are higher than expected, it could signal increased thyroid activity, various thyroid disorders, or in cancer survivors, the possibility that some thyroid tissue or cancer cells remain active. For anyone monitoring thyroid health—whether you've had thyroid surgery, are dealing with thyroid nodules, or have a family history of thyroid problems—this test helps your healthcare team stay one step ahead, ensuring treatments are working effectively and catching any changes before they become bigger concerns.
Reviewed by Dr. Vu Tran Bloody Good’s Chief Medical Officer
You may benefit from the Thyroglobulin Blood Test
Essential for individuals with thyroid cancer history, post-thyroid surgery, thyroid disorders, or anyone needing comprehensive thyroid tissue and cancer monitoring assessment.
Enlarged thyroid gland or goiter
Feeling tired all the time
Always feeling cold even in warm weather
Family history of thyroid cancer
Age-appropriate cancer screening
Difficulty swallowing solids
Feeling like something is stuck in throat
How to prepare
No special preparation required. Inform healthcare provider of thyroid medications, recent thyroid procedures, and any factors that might affect thyroglobulin levels or interpretation.
Understanding results
Results show thyroglobulin levels compared to normal ranges. Elevated levels may indicate thyroid tissue activity, cancer recurrence, or thyroid disorders requiring further evaluation.
After the test
Address abnormal thyroglobulin through thyroid cancer surveillance, additional imaging studies, treatment adjustments, and specialized thyroid cancer care. Work with oncologists and endocrinologists for cancer monitoring.
Frequently Asked Questions
Thyroglobulin is a protein made only by thyroid tissue; it serves as a tumor marker for thyroid cancer monitoring and assessment of thyroid tissue activity.
Elevated levels may indicate thyroid tissue activity, thyroid disorders, or in thyroid cancer patients, potential cancer recurrence requiring further evaluation.
Testing is primarily used for thyroid cancer patients to monitor treatment effectiveness and detect recurrence, and for evaluating certain thyroid disorders.
For thyroid cancer patients, testing frequency depends on cancer stage and treatment, typically every 6-12 months initially, then annually if stable.
Levels can be affected by thyroid tissue presence, thyroid medications, recent procedures, and thyroid antibodies that may interfere with testing.
Very low or undetectable levels are expected after complete thyroid removal and successful cancer treatment, indicating no residual thyroid tissue.
Bloody Good is a single portal for ordering, tracking, and reviewing on-demand health testing.
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If your test needs fasting, we’ll include that in your instructions after you order. Fasting usually means no food for 8–12 hours, but water is fine.
Just your pathology referral form (we email it to you)
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