Experiencing chest discomfort, fatigue, or suspected tissue damage and want assessment of cellular health for disease detection and monitoring?
The Lactate Dehydrogenase (LDH) Test measures an enzyme found in many tissues, including the heart, liver, muscles, and blood cells. High LDH levels may be linked to tissue damage, liver or muscle disease, or certain cancers, while normal levels usually indicate healthy cell function.
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The Lactate Dehydrogenase (LDH) Test measures an enzyme found in many tissues, including the heart, liver, muscles, and blood cells. High LDH levels may be linked to tissue damage, liver or muscle disease, or certain cancers, while normal levels usually indicate healthy cell function.
Think of LDH (lactate dehydrogenase) as your body's cellular damage detector – an enzyme that acts like a smoke alarm for your tissues. This hardworking enzyme is naturally found in nearly every cell throughout your body, quietly helping produce the energy your cells need to function. When cells become damaged or destroyed – whether from injury, disease, or other health issues – they release LDH into your bloodstream, creating a measurable signal that something may need attention.
The LDH test captures this cellular "distress signal" by measuring the amount of this enzyme in your blood, giving healthcare providers valuable insight into your tissue health. Elevated levels can indicate various conditions affecting your heart, liver, lungs, muscles, or blood cells, making it particularly useful for investigating symptoms like unexplained chest pain, persistent fatigue, or shortness of breath. While LDH doesn't pinpoint exactly what's wrong (think of it as a general health indicator rather than a specific diagnosis), it serves as an important piece of the puzzle that helps guide further testing and treatment decisions, especially for monitoring conditions like heart problems, liver disease, blood disorders, or tracking how well treatments are working over time.
You may benefit from the Lactate Dehydrogenase (LDH) Blood Test
Essential for individuals with suspected tissue damage, blood disorders, organ dysfunction, or anyone needing comprehensive cellular health assessment.
Chest pain or tightness
Muscle pain after exercise that lasts days
Extreme fatigue that doesn't improve with rest
Annual physical exam
How to prepare
No special preparation required. Inform healthcare provider of all medications, recent physical activity, and any conditions that might affect LDH levels or interpretation.
Understanding results
Results show LDH levels compared to normal ranges. Elevated levels indicate tissue damage requiring further evaluation to identify the source and underlying cause.
After the test
Address elevated LDH through investigation of underlying causes, treatment of specific conditions causing tissue damage, and monitoring of disease progression or recovery.
Frequently Asked Questions
LDH is an enzyme found in most body tissues; elevated blood levels indicate cellular damage or death in various organs or tissues.
Conditions include heart attack, liver disease, blood disorders, cancers, muscle injury, lung problems, and infections causing tissue damage.
Symptoms may include chest pain, fatigue, shortness of breath, muscle weakness, or other signs suggesting tissue damage or organ dysfunction.
No, LDH is found in many tissues, so elevated levels require additional testing to determine the specific source of tissue damage.
Treatment focuses on addressing the underlying condition causing tissue damage rather than the LDH elevation itself.
Yes, LDH levels typically decrease as tissue damage heals or underlying conditions are successfully treated.
Reviewed by Dr. Vu Tran Bloody Good’s Chief Medical Officer
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